Oral Presentation Society of Obstetric Medicine of Australia and New Zealand ASM 2023

Pregnancy Management in Women with Kidney Transplant  (#11)

Nishanta Tangirala 1 2 3
  1. Central Northern Adelaide Renal and Transplantation Services (CNARTS), Adelaide, South Australia
  2. Women's and Children's Hospital Foundation, North Adelaide
  3. Nephrology, Lyell McEwin Hospital, Adelaide, SA

In most women with a kidney transplant, fertility is spontaneously restored within a few months (1). This offers the chance for transplanted women to experience parenthood. Pregnancy is feasible for women with a kidney transplant and increasingly a more common reality (2). However, these pregnancies remain complex and high risk - often complicated by preterm delivery, pregnancy-induced hypertension, preeclampsia, caesarean delivery, miscarriage and gestational diabetes (2,3). Babies born to women with kidney transplantation are also significantly affected, with twice the odds of adverse outcomes compared to babies not born to women on kidney replacement therapy (3). With advancements in obstetric and multidisciplinary care, outcomes continue to improve. However, navigating safer pathways to pregnancy for women with kidney transplantation remains key and is an important skill for health care providers. 

In this session, we present the South Australian-Northern Territory Protocol for Preconception and Pregnancy Management in Women with Kidney Transplantation - discussing the main potential issues of pregnancy in kidney transplantation. The session will focus on: preconception counselling, maternal medical management during pregnancy and choice of immunosuppressive agents. 

This protocol was formulated by a South Australian writing and consumer group who have clinical and research experience in obstetric nephrology. 

 

 

 

 

  1. Hewawasam E, Davies C, Gulyani A, Li Z, Clayton P, Sullivan E, McDonald S, Jesudason S. Factors influencing fertility rates in Australian women receiving kidney replacement therapy: analysis of linked Australia and New Zealand Dialysis and Transplant Registry and perinatal data over 22 years. Nephrology Dialysis and Transplantation. 2022.
  2. Ponticelli C, Zaina B, Moroni G. Planned pregnancy in Kidney Transplantation. A Calcultated Risk. J Per Med. 2021.
  3. Hewawasam E, Davies CE, Li Z, Clayton P, Sullivan E, McDonald SP, Jesudason S. Determinants of Perinatal Outcomes in Dialysed and Transplanted Women in Australia. Kidney International Reports. 2022.